Dr. Salim Merali working in the lab

Proteomics Facility

Use science without limits.

Proteomics is widely and successfully used in drug discovery, disease treatment research, and biomarker discovery. These intricate studies require high levels of quality controls, adequate instrumentation, and expertise to analyze thousands of proteins to obtain meaningful results. 

We embrace these principles and invest continuously by recruiting experts, procuring hi-tech equipment, and regularly revising protocols and procedures. We are experts in proteomics, tissue microanalysis, and relevant bioinformatics platforms. Research at the facility has led to numerous scientific discoveries and has been extensively published and cited. 

The facility assists researchers with state-of-the-art mass spectrometry expertise, practice, and instrumentation to address health-related scientific questions concerning our community. Researchers study the proteome, including modifications made to a particular set of proteins produced by a cell, tissue, organism, or system. 

Understand our origin

Located at the Temple School of Pharmacy, the facility was established in 2005 as part of the Temple University Researcher Development Program and provides accessible proteomics capability for biological and biomedical research to support faculty within Temple and outside institutions, including pharmaceutical companies.

Find what you need

  • Protein expression profiling
  • Protein identification
  • Post-translational modification characterization
  • Isolation of individual cells from tissues
  • Protein and peptide separations 
  • Generation of high fidelity data for biomarker discovery, drug targets, identification of molecular transducers of disease
  • Performance of multiple protein assays, including modified iST, GeLCMs, SILAC, post-translational modifications, MRM/SRM, iTRAQ, DARTS, protein-protein interactions

Explore our tools

  • TSQ Quantum Ultra™ Triple Quadrupole Mass Spectrometer
  • Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer
  • Orbitrap Elite™ Hybrid Ion Trap-Orbitrap Mass Spectrometer with ETD
  • Autoflex II TOF/TOF System
  • WES ProteinSimple System
  • Beckman Coulter P/ACE MDQ capillary electrophoresis "nanotechnology" system with dual wavelength laser-induced fluorescence (LIF) detection system
  • Waters HPLC System (2795)
  • Leica VT1200 S - Vibrating Blade Microtome
  • Veritas Microdissection Instrument with LCM, Laser Cutting and Fluorescence Detection

Staff

  • Temple University Logo

    Carmen Merali

    • School of Pharmacy

      • Pharmaceutical Sciences

        • Research Scientist & Lab Manager

  • Salim Merali, PhD

    Salim Merali, PhD

    • School of Pharmacy

      • Pharmaceutical Sciences

        • Associate Dean & Laura H. Carnell Professor

          Programs

          • Moulder Center for Drug Discovery Research